Module 2 – Overview and introduction to organoids

Navigation
1. Model systems in pancreatic cancer
2. 3D culture systems
3. Definition of terms
4. Organoid introduction
5. Importance of the matrix
6. Matrix influence on morphology and function
7. Stem cell contribution
8. Pancreatic organoids
9. Culture media composition
10. Immunocompromised mice
11. PDA progression
12. Murine organoid transplants
13. Mouse ODI to track immunoevolution of PDA
14. Changes in immune landscape
15. Establishment of human organoids
16. Pancreatic Ductal organoids
17. Different organoid technologies
18. Application: drug screening
Thank you
logo-courses-1
Previous Lesson
Next Lesson

3. Definition of terms

Module 2 – Overview and introduction to organoids 3. Definition of terms

References:
1. Xu H, Jiao Y, Qin S, Zhao W, Chu Q, Wu K. Organoid technology in disease modelling, drug development, personalized treatment and regeneration medicine. Exp Hematol Oncol. 2018 Dec 5;7:30. doi: 10.1186/s40164-018-0122-9. eCollection 2018. Review. PubMed PMID: 30534474; PubMed Central PMCID: PMC6282260.
2. Simian M, Bissell MJ. Organoids: A historical perspective of thinking in three dimensions. J Cell Biol. 2017 Jan 2;216(1):31-40. doi: 10.1083/jcb.201610056. Epub 2016 Dec 28. Review. PubMed PMID: 28031422; PubMed Central PMCID: PMC5223613.
3. Davies, J. A. Chapter 1 – Organoids and mini-organs: Introduction, history, and potential. Organs and organoids 2018

Previous Lesson
Back to Course
Next Lesson
Login
Accessing this course requires a login. Please enter your credentials below!

Lost Your Password?
logo-courses-1